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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha : |
31/03/2021 |
Actualizado : |
31/03/2021 |
Tipo de producción científica : |
Trabajos en Congresos/Conferencias |
Autor : |
MISZTAL, I.; WANG, H.; AGUILAR, I.; LEGARRA, A.; TSURUTA, S.; LOURENCO, D.; FRAGOMENI, B. O.; ZHANG, X.; MUIR, W. M.; CHENG, H. H.; OKIMOTO, R.; WING, T.; HAWKEN, R. R.; ZUMBACH, B.; FERNANDO, R. |
Afiliación : |
IGNACY MISZTAL, University of Georgia, Athens, GA, USA; H. WANG, Genus PIC, Hendersonville, TN; IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; ANDRÉS LEGARRA, INRA, Toulouse, France; S. TSURUTA, University of Georgia, Athens, GA, USA; D.A.L. LOURENCO, University of Georgia, Athens, GA, USA; B. O. FRAGOMENI, University of Georgia, Athens, GA, USA; X. ZHANG, University of Georgia, Athens, GA, USA; W. M. MUIR, Purdue University, West Lafayette, IN, USA; H. H. CHENG, Cobb-Vantress Inc., Siloam Springs, AR, USA; R. OKIMOTO, Cobb-Vantress Inc., Siloam Springs, AR, USA; T. WING, Cobb-Vantress Inc., Siloam Springs, AR, USA; R. R. HAWKEN, Cobb-Vantress Inc., Siloam Springs, AR, USA; B. ZUMBACH, Cobb-Vantress Inc., Siloam Springs, AR, USA; R. FERNANDO, Department of Animal Science, Iowa State University, Ames, IA, USA. |
Título : |
GWAS using ssGBLUP. |
Complemento del título : |
Volume Species Breeding: Poultry, 325. |
Fecha de publicación : |
2014 |
Fuente / Imprenta : |
In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 10., Vancouver, BC, Canada, August 17-22, 2014. p.325. |
Idioma : |
Inglés |
Contenido : |
ABSTRACT.
This study aimed to compare results of genome-wide associations obtained from various methodologies for GWAS when applied to two lines of broiler chicken. Each line contained >250k birds with 3 traits and 5k SNP60k genotypes. Methods included single-step GWAS, single marker model and BayesB. Mannhattan plots were based on variances of 20-SNP segments, as shorter segments produced noisy plots. Only a few segments explained >1 % of the additive variance. One segment explained >20% variance in BayesB but 3% with ssGWAS and <1% with a single marker model. In two lines, no major segment overlapped for any trait. When analyses used slices of generations (1-3,2-4,3-5,1-5), variances for the same segment varied greatly. The plots were more distinct with a new data set that included >16k genotypes, but no segment explained >1% of the variance. Strength of associations strongly depends on methodologies and details of implementations. |
Palabras claves : |
GWAS; SNP variance; SsGBLUP. |
Asunto categoría : |
L10 Genética y mejoramiento animal |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/15454/1/Misztal-et-al.-2014.WCGALP.pdf
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Marc : |
LEADER 01803nam a2200313 a 4500 001 1061930 005 2021-03-31 008 2014 bl uuuu u01u1 u #d 100 1 $aMISZTAL, I. 245 $aGWAS using ssGBLUP.$h[electronic resource] 260 $aIn: Proceedings of the World Congress on Genetics Applied to Livestock Production, 10., Vancouver, BC, Canada, August 17-22, 2014. p.325.$c2014 520 $aABSTRACT. This study aimed to compare results of genome-wide associations obtained from various methodologies for GWAS when applied to two lines of broiler chicken. Each line contained >250k birds with 3 traits and 5k SNP60k genotypes. Methods included single-step GWAS, single marker model and BayesB. Mannhattan plots were based on variances of 20-SNP segments, as shorter segments produced noisy plots. Only a few segments explained >1 % of the additive variance. One segment explained >20% variance in BayesB but 3% with ssGWAS and <1% with a single marker model. In two lines, no major segment overlapped for any trait. When analyses used slices of generations (1-3,2-4,3-5,1-5), variances for the same segment varied greatly. The plots were more distinct with a new data set that included >16k genotypes, but no segment explained >1% of the variance. Strength of associations strongly depends on methodologies and details of implementations. 653 $aGWAS 653 $aSNP variance 653 $aSsGBLUP 700 1 $aWANG, H. 700 1 $aAGUILAR, I. 700 1 $aLEGARRA, A. 700 1 $aTSURUTA, S. 700 1 $aLOURENCO, D. 700 1 $aFRAGOMENI, B. O. 700 1 $aZHANG, X. 700 1 $aMUIR, W. M. 700 1 $aCHENG, H. H. 700 1 $aOKIMOTO, R. 700 1 $aWING, T. 700 1 $aHAWKEN, R. R. 700 1 $aZUMBACH, B. 700 1 $aFERNANDO, R.
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INIA Las Brujas (LB) |
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Registros recuperados : 4 | |
2. | | MISZTAL, I.; AGUILAR, I.; TSURUTA, S.; SÁNCHEZ, J.P.; ZUMBACH, B. Studies on heat stress in dairy cattle and pigs. Volume Special topics: Animal breeding and the environmental challenges - Lecture Sessions, 0625. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 9., Leipzig, Germany, August 1-6, 2010. p. 0625.Tipo: Trabajos en Congresos/Conferencias |
Biblioteca(s): INIA Las Brujas. |
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3. | | LOURENCO, D.A.L.; FRAGOMENI, B.O.; TSURUTA, S.; AGUILAR, I.; ZUMBACH, B.; HAWKEN, R.J.; LEGARRA, A.; MISZTAL, I. Accuracy of estimated breeding values with genomic information on males, females, or both: An example on broiler chicken. Genetics Selection Evolution, 2015, v. 242, p. 47-56. OPEN ACCESS. Article history: Received: 14 October 2014 / Accepted: 22 June 2015 / Published: 02 July 2015.Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
Biblioteca(s): INIA Las Brujas. |
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4. | | MISZTAL, I.; WANG, H.; AGUILAR, I.; LEGARRA, A.; TSURUTA, S.; LOURENCO, D.; FRAGOMENI, B. O.; ZHANG, X.; MUIR, W. M.; CHENG, H. H.; OKIMOTO, R.; WING, T.; HAWKEN, R. R.; ZUMBACH, B.; FERNANDO, R. GWAS using ssGBLUP. Volume Species Breeding: Poultry, 325. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 10., Vancouver, BC, Canada, August 17-22, 2014. p.325.Tipo: Trabajos en Congresos/Conferencias |
Biblioteca(s): INIA Las Brujas. |
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Registros recuperados : 4 | |
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